Cannabis Science Brand Products To Be Released October 2011 - Successful Cancer Treatments With Cannabis Extracts

DENVER, Sep 26, 2011 (BUSINESS WIRE) -- Cannabis Science, Inc. CBIS , a pioneering US biotech company developing pharmaceutical cannabis products, is pleased to announce shareholder guidance on the upcoming release of the first Cannabis Science brand of products. Cannabis extract-based products will initially be made available to licensed medical marijuana patients in Colorado. The Company is excited to announce that its proprietary brand of pharmaceutical products is nearing commercialization.

It is expected that in October 2011, Cannabis Science will contract the production and manufacturing of its branded products for distribution and sale through selected Colorado State licensed dispensaries. The first products will address the needs of patients choosing to use concentrated cannabis extracts to treat their ailments. For example, Cannabis Science has frequently been contacted by cancer patients seeking extract-based formulations for topical or internal use. Cannabis Science is responding to these patient requests for quality products. In the very near future, Cannabis Science will announce details of availability.

In light of the accumulating anecdotal reports of the successful cancer treatments with cannabis extracts, the Company will continue to keep patients updated on current peer-reviewed scientific literature supporting the historical and modern use of cannabis to treat "tumors". Unlike conventional methods, cannabis medicines have an outstanding safety profile allowing patients in states with medical marijuana laws to safely make informed decisions to legally self-administration of various cannabis-based preparations.

Dr. Robert Melamede Ph.D., Cannabis Science president & CEO, stated, "Based on our continued commitment to educate people about the medical value of cannabis, and increasing shareholder value with revenues, releasing these products is a natural progression for us as the world has it's cannabis awakening. Cannabis Science believes everyone has the right to fair and equal access to cannabis-based treatments worldwide.

We believe marijuana prohibition is unconstitutional. It denies people Life, Liberty and the pursuit of Happiness. Additionally, furthermore, the current legal status violates the equal protection clause. People have legal access to cannabis-based medicines in some states, while others are criminal for using their medicine. Cannabis Science will remedy this situation through educating the masses and by taking our cannabis-based products through the FDA process for nationwide distribution. Eventually, all Americans will have access to a safe and effective FDA approved medicine regardless of which state they live in. To maintain that marijuana is a dangerous, addictive drug with no medical value is scientifically absurd. Cannabis medicines, with no effective lethal dose, are far safer than aspirin, acetaminophen, and most other OTC drugs that kill thousands of Americans every year.

About Cannabis Science, Inc.

Cannabis Science, Inc. is at the forefront of pharmaceutical grade medical marijuana research and development. The Company works with world authorities on phytocannabinoid science targeting critical illnesses, and adheres to scientific methodologies to develop, produce and commercialize phytocannabinoid-based pharmaceutical products. In sum, we are dedicated to the creation of cannabis-based medicines, both with and without psychoactive properties, to treat disease and the symptoms of disease, as well as for general health maintenance.

Forward Looking Statements; This Press Release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Act of 1934. A statement containing works such as "anticipate," "seek," intend," "believe," "plan," "estimate," "expect," "project," "plan," or similar phrases may be deemed "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Some or all of the events or results anticipated by these forward-looking statements may not occur. Factors that could cause or contribute to such differences include the future U.S. and global economies, the impact of competition, and the Company's reliance on existing regulations regarding the use and development of cannabis-based drugs. Cannabis Science, Inc. does not undertake any duty nor does it intend to update the results of these forward-looking statements.

SOURCE: Cannabis Science, Inc.

Cannabis Science Inc.
Robert Kane
Investor Relations Management
info@cannabisscience.com

The Fountain of Youth: Researchers Identify Mechanism That Seems to Protect Brain from Aging

 copyright University of Bonn

Researchers from the Universities of Bonn and Mainz have discovered a mechanism that seems to protect the brain from aging. In experiments with mice, they switched off the cannabinoid-1 receptor. As a consequence, the animals showed signs of degeneration -- as seen in people with dementia -- much faster.

The research results are presented in a current issue of the Proceedings of the National Academy of Sciences (PNAS).

Humans are getting older and older, and the number of people with dementia is increasing. The factors controlling degeneration of the brain are still mostly unknown. However, researchers assume that factors such as stress, accumulation of toxic waste products as well as inflammation accelerate aging. But, vice versa, there are also mechanisms that can -- like a bodyguard -- protect the brain from degenerating, or repair defective structures.

Researchers from the Universities of Bonn and Mainz have now discovered a hitherto unknown function of the cannabinoid-1 receptor (CB1). A receptor is a protein that can bind to other substances, triggering a chain of signals. Cannabinoids such as THC -- the active agent in cannabis sativa -- and endocannabinoids formed by the body bind to the CB1 receptors. The existence of this receptor is also the reason for the intoxicating effect of hashish and marijuana.

Not only does the CB1 receptor have an addictive potential, but it also plays a role in the degeneration of the brain. "If we switch off the receptor using gene technology, mouse brains age much faster," said Önder Albayram, principal author of the publication and a doctoral student on the team of Professor Dr. Andreas Zimmer from the Institut für Molekulare Psychiatrie at the University of Bonn. "This means that the CB1 signal system has a protective effect for nerve cells."

Mice prove their brain power in a pool

The researchers studied mice in different age categories -- young six week old animals, middle-aged ones at five months, and those of an advanced age at 12 months. The animals had to master various tasks -- first, they had to find a submerged platform in the pool. Once the mice knew its location, the platform was moved, and the animals had to find it again. This was how the researchers tested how well the rodents learned and remembered.

The animals in which the CB1 receptor had been switched off (the knock-out mice) clearly differed from their kind. "The knock-out mice showed clearly diminished learning and memory capacity," said Privatdozent Dr. Andras Bilkei-Gorzo from Professor Zimmer's team, who led the study. So, animals that did not have the receptor were less successful in their search for the platform. "In addition, they showed a clear loss of nerve cells in the hippocampus," he explained further. This part of the brain is the central area for forming and storing information. In addition, the researchers found inflammation processes in the brain. As the mice advanced in age, the degenerative processes became increasingly noticeable.

Amazing parallels with the human brain

The animals with the intact CB1 receptor, to the contrary, did clearly better with regard to their learning and memory capabilities, as well as the health of their nerve cells. "The root cause of aging is one of the secrets of life," commented Albayram. This study has begun to open the door to solving this enigma. The processes in the mouse brains have a surprising number of parallels with age-related changes in human brains. So, the endocannabinoid system may also present a protective mechanism in the aging of the human brain.

The principal author cautioned, "This will require additional research." The scientists would like to better understand the mechanism by which CB1 receptors protect the brain from inflammation processes. And based on these signal chains, it might then be possible to develop substances for new therapies. ScienceDaily (July 13, 2011) — http://www.sciencedaily.com/releases/2011/07/110712093856.htm

US National Cancer Institute Updates, Confirm Successful Cancer Treatments with Medical Cannabis - Encod.org

Cannabis Science, Inc. (OTCBB:CBIS), a pioneering US biotech company developing pharmaceutical cannabis products, is pleased to report a government released update on cancer treatments using medical cannabis (marijuana)

http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional and cancer.gov, updated March 17, 2011, summarizing how the treatment of cancer with cannabinoids goes beyond the simple treatment of symptoms and side effects by exhibiting possible direct anti tumor activities.

“In the practice of integrative oncology, the health care provider may recommend medicinal Cannabis not only for symptom management but also for its possible direct antitumor effect.”

This summary contains the following key information:

• Cannabis has been used for medicinal purposes for thousands of years prior to its current status as an illegal substance.
• Chemical components of Cannabis, called cannabinoids, activate specific receptors found throughout the body to produce pharmacologic effects, particularly in the central nervous system and the immune system.
• Cannabinoids may have benefits in the treatment of cancer-related side effects.
• The potential benefits of medicinal Cannabis for people living with cancer include antiemetic effects, appetite stimulation, pain relief, and improved sleep.
• Though no relevant surveys of practice patterns exist, it appears that physicians caring for cancer patients who prescribe medicinal Cannabis predominantly do so for symptom management.
• Unlike other commonly used drugs, cannabinoids are stored in adipose tissue and excreted at a low rate (half-life 1–3 days).
• Even abrupt cessation of cannabinoid intake is not associated with rapid declines in plasma concentrations that would precipitate severe or abrupt withdrawal symptoms or drug cravings.

Robert Melamede, Ph.D., Cannabis Science’s CEO stated, “As we’ve previously reported, one of the most interesting findings that has emerged since the discovery of the endocannabinoid system (marijuana like compounds produced by humans, and all vertebrates) is that cannabinoids have profound cancer-killing and anti-metastatic properties. There is strong scientific support, demonstrated in tissue culture and animal studies, of the potent cancer killing properties of cannabinoids for such deadly cancers as glioma, lung cancer, breast and prostate cancer, leukemias and lymphomas, and as well as skin cancers.

Currently the federal government prohibitionist position on cannabis is hindering the medical community by delaying vitally important clinical cannabis research. I was quite elated when I recently saw that the NCI posted on their webpage “In the practice of integrative oncology, the health care provider may recommend medicinal Cannabis not only for symptom management but also for its possible direct antitumor effect.” I foolishly thought that finally there would be official recognition of the modern peer reviewed science that shows the cancer killing properties of cannabinoids. Sadly, this statement was removed, without comment, within hours of its posting.”

Dr. Melamede goes on to say “Clinical trials are desperately needed. Cannabis Science is actively working on arrangements that will allow us to perform the necessary clinical trials to verify, or not, the numerous anecdotal reports demonstrating what appears to be cancer cures. These observations are occurring with greater frequency since numerous states have legalized the medical use of cannabis. Cannabis in various forms has been used by different cultures for thousands of years as a viable medicine for numerous ailments. In fact, some biblical translations even indicate that cannabis (keneh bosem) was a component of the “Holy Anointing Oil.” Current cannabis science simply provides evidence that supports the widespread historical use of oral, cannabis-based medicines that was driven by it’s success in treating illnesses.”

Published on Thursday 1 September 2011 00:19, by Martin Steldinger . Modified on Thursday 1 September 2011 00:18
http://www.encod.org/info/US-National-Cancer-Institute.html#.TnwWQPXEvbJ.blogger

Cannabis should be licensed and sold in shops, expert says

Leading cannabis researcher calls for legalisation with controls similar to alcohol and tobacco.

 Cannabis is no more dangerous than tobacco or alcohol, according to Professor Pertwee.

Cannabis for recreational use should be available in shops under similar restrictions to those used to control the sale of alcohol and tobacco, according to Britain's leading expert on the drug.

Under one scenario, people would be able to apply for a licence to buy cannabis products once they reach the age of 21, provided they have the approval of a doctor, he said.

The drug would be regulated by a body that ensures the quality and safety of the products before they go on sale.

A rethink of the laws surrounding cannabis and related products was necessary to take cannabis out of the hands of criminals, said Roger Pertwee, professor of neuropharmacology at Aberdeen University.

In the 1970s, Pertwee co-discovered THC, the active ingredient in cannabis.

Speaking ahead of a talk this week at the British Science Festival in Birmingham, Pertwee said: "In my view, we don't have an ideal solution yet to deal with recreational cannabis. We should consider licensing and marketing cannabis and cannabis products just as we do alcohol and tobacco.

"At the moment, cannabis is in the hands of criminals, and that's crazy. We're allowed to take alcohol, we're allowed to smoke cigarettes. Cannabis, if it's handled properly, is probably not going to be any more dangerous than that."

The government upgraded cannabis to a class B drug late last year against the advice of the Advisory Council on the Misuse of Drugs. The council's chairman, Professor David Nutt, was sacked after criticising the government's drugs policy, a move that prompted five others to resign in protest.

Possession of class B drugs, which include amphetamines, such as speed and barbiturates, carries a maximum penalty of five years in prison plus a fine. Dealing the drugs can lead to a 14-year prison sentence. The most recent Home Office figures show there are 158,000 convictions for cannabis possession a year.

Pertwee said he wanted to reopen the debate on cannabis, saying he favoured legalisation if the drug was well regulated. He added that healthier alternatives to smoking cannabis were available.

Outlawing the drug forced users to either grow it illicitly or buy it from an illegal dealer. "They have no idea what the composition is, what has been added to it, and they are at risk of being invited to take other drugs," he said.

Attempts to relax the ban on cannabis have been countered by concerns that it can cause schizophrenia in a minority of people who are susceptible to the condition. Pertwee said it might be possible for doctors to assess people's backgrounds and risk of mental health problems before allowing them to buy a cannabis licence.

"You would need a minimum age of 21, but I would go further: that you have to have a licence. You have to have a car licence, you have to have a dog licence; why not a cannabis licence, so you can only take it if it's medically safe for you to do so?" he said.

Nutt, who is a professor of neuropsychopharmacology at Imperial College London, said: "I welcome this attempt by the UK's leading expert on cannabis to bring rationality to the debate on its legal status.

"As cannabis is clearly less harmful than alcohol, criminalisation of people who prefer this drug is illogical and unjust. We need a new regulatory approach to cannabis. The Dutch coffee-shop model is one that has been proven to work but some of Professor Pertwee's new suggestions may well have extra benefits and should be actively debated."

http://www.guardian.co.uk/science/2010/sep/14/cannabis-licence-legalisation-pertwee

THC and cannabinoids are antioxidants

I was looking around on pubmed.com and was somewhat surprised to find out that THC and cannabidiol, the primary cannabis cannabinoids, are powerful neuroprotective antioxidants. I also stumbled upon an article that describes how cannabidiol is a medication-strength antipsychotic, and counteracts the anxiety or paranoia that can be caused by THC.

THC and cannabidiol are powerful anti-inflammatory antioxidants. A 2007 scientific article written in part by the National Institutes of Health states that “cannabinoid, as components of the Cannabis sativa (marijuana) plant, are known to exert potent anti-inflammatory, immunomodulatory and analgesic effects...” “Cannabidiol, one of the most abundant cannabinoids of Cannabis sativa with reported antioxidant, antiinflammatory, and immunomodulatory effects is well tolerated without side effects when chronically administered to humans...” The study concluded that cannabidiol can help to protect against diabetic comlications and atherosclerosis and that “this is particularly engouraging in light of the excellent safety and tolerability profile of cannabidiol in humans”. Pubmed ID 17384130
Another study, titled “Cannabidiol and THC are neuroprotective antioxidants” found that “cannabidiol protected neurons to a greater extent than either of the dietary antioxidants, alpha-tocopherol or ascorbate (vitamin C).” And that the antioxidant effects seen in the studied cannabinoids is “a common property of classical cannabinoid structures”. “The psychoactive principle of Cannabis, THC, also blocked glutamate neurotoxicity with similar potency to cannabidiol.” Pubmed ID 9653176
An additional study, “Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity” showed that cannabidiol can indeed protect neurons from alcohol-induced damage. Pubmed ID 15878999
Another 2007 study found that THC inhibits lung cancer cell growth, migration, and metastasis. Pubmed ID 17621270
There is also the argument that cannabis causes psychosis. While pure THC has been shown to cause acute psychosis, cannabidiol is a powerful antipsychotic and negates the negative effects of THC, as stated by the 2006 article “Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug”. Pubmed ID 16612464 

by Sombrero

http://boards.cannabis.com/medicinal-cannabis-health/127362-thc-cannabinoids-antioxidants.html

Medical Cannabis to treat Autism

HYDROPONIC OR ORGANIC What's the difference?

I am sick of seeing uneducated people telling me Hydroponics is bad. Im here to show you it is NOT bad just different.

HYDROPONIC OR ORGANIC  What's the difference? by Roger H. Thayer

I'd like to have a dollar for each time I've been asked, "Is it organic?", since I started in the hydroponics business in 1972, I'd be rich! Is hydroponics organic? Is it chemical? What are the similarities and the differences? These questions have never really been answered to the satisfaction of most people as evidenced by the fact that I am asked the same questions today as often as I was nearly 20 years ago. Many people are confused by the word "organic" as it means different things to different people.

To the farmer, the word organic means no pesticides or herbicides. No potentially toxic or hazardous materials are to be used on crops to control bugs, weeds and diseases. To the gardener, the word usually means all of these things, plus that no unnatural or manmade chemicals are to be used. Only "organic" fertilizers and natural controls. They must: be made by nature, not by man.

To the chemist, on the other hand, the word "organic" means something totally different. In chemistry there are two distinct branches: inorganic and organic chemistry. Inorganic chemistry deals with non-living materials.

Organic chemistry focuses on the carbon and carbon containing compounds, typically associated with life. Biologists and botanists, and others who deal with the life sciences, are stuck in the middle. When they deal with chemists and other scientists, they have to adhere to the chemical definition of organic. When they talk to the farmer or gardener, they have to talk in different terms. To them, organic means "natural," not carbon based. They can say one thing, but really mean something else.

There is really no difference between an atom, mineral or the element itself. What matters is whether or not they are in a form that is non-harmful and that can used by plants. If so, they are beneficial whether natural or manmade. Plants do not take up carbon at the roots, they get all they need from the CO₂ in the air, so the term "organic gardening" is confusing. The same minerals are needed in either hydroponic or organic growing. These minerals are provided to plants in the organic garden as they are released from organic matter by the action of microbes, worms and bacteria. In hydroponics, these same elements are provided by water soluble mineral salts.

In hydroponics, mineral elements are provided by the use of mineral salts. These may be either naturally derived of manmade, but most have been purified and processed so that they are water soluble and in a form that can be used by plants. Many start out as mined minerals or naturally concentrated deposits that are dissolved and processed into compounds with a definite molecular structure and composition. In the refining process, these mineral salts are usually purified to remove heavy metal contaminants and toxic substances that could harm plants or people. Since the chemical composition is precisely known, different mineral salts can be combined to form a balanced hydroponic nutrient. When dissolved in the proper proportions with a good quality water, a hydroponic nutrient solution can provide all of the mineral elements needed for plant growth without soil. By its nature, the hydroponic methods eliminates much of the uncertainty and guesswork found in organic growing. Some adjustments are normally made for proper pH, controlling nutrient concentrations (parts per million) and to maintain balance between the nutrients provided. These are usually easy adjustments and within the control of the grower. In a well-built hydroponic installation, all conditions are controllable so optimum plant growth can be achieved, even surpassing nature.

But is it organic? Can a hydroponic plant nutrient be classified as organic? Probably not, unless you go back to the chemical definition of the word, that is a substance that contains carbon. By this definition, many "chemical" nutrient formulas would be considered organic. These include the chelated trace elements as well as urea, which contains carbon in the form (NH₂)CO₂. It is also possible to define a hydroponic nutrient solution as organic by drawing on the definition many people use that organic is "natural".

Most of the mineral elements used in hydroponics start out as mined rock or mineral deposits which are as natural as the earth itself. The important point is that it is not the elements that are different in organic and hydroponic growing, it is how these elements are obtained and delivered to the plant.

Pros and cons. There are definite advantages and disadvantages to both organic and hydroponic growing. land is still available for conventional agriculture. With proper techniques and care, organic growing can yield good, nutritious crops on a large scale with minimal expense, although it can be labor intensive. Organic growing has an element of uncertainty, as already mentioned, but with care and knowledge, that can be kept to a minimum. Still, optimal mineral and element composition is going to involve guesswork unless expensive chemical soil analysis is routinely done and soil amendments are used to correct deficiencies. Most of the amendments used in modern agriculture happen to be the exact same mineral salts that are used in most hydroponic nutrient formulas. The advantages of hydroponic growing are increased yield through complete nutritional and environmental control, the absence of competing weeds and soil-borne diseases, increased crop density and reduced water consumption. With recycling systems, hydroponics uses one-tenth the amount of water used by irrigated agriculture. Growing media are easily sterilized and conditions can be altered quickly to suit specific crops or the growth stage of a particular crop, such as during flowering or fruit production.

The main disadvantage is the initial set-up cost. The cost of a good installation is fairly high, but if quality materials are used that cost can be spread out over many years. What about using hydroponic nutrients in an organic or soil garden! There are many advantages to this kind of hybrid application, combining organic compost with hydroponic nutrients similar to Mittleider Gardening. Care must be taken not to overdose the plants with such a system. If a full-strength chicken manure is used with a full-strength hydroponic solution the plants can be burned. Handled properly the system could eliminate mineral deficiencies. Plants grow faster and healthier as long as pH, drainage and water/nutrient retention are adequate. Because the plants are healthier they are able to ward off insects and diseases, further enhancing yield.

Hydroponics University

Hydro-U is a service of Simply Hydroponics and Organics On-line as part of our consumer education program. We welcome your feedback. Your input is what makes this site work. Please contact us with any questions or ideas.

http://www.simplyhydro.com/hydvsorg.htm

If the truth won't do, then something is wrong!

Those were the furious words of my Grandfather to my Mother. I had walked in from joyfully stuffing my face with red raspberries in the garden, straight into "war zone"! My gentle Grandfather in a fury, his hand raised! Mom was just beginning to shrink back away from him. They saw me and quickly sent me away. But it was too late, the scene and the words were seared into my 5-year-old brain. That was over 55 years ago, but I still remember it clearly. My Grandfather was a Minister, one very short step away from God in my young mind. It was one of those life changing moments. It is still rare for me to tell a lie. I never found out what my Mother's lie was.

As I child, I suffered a traumatic head injury. Another child tried to murder me with a hammer. I was left with frequent migraines. At 19, like many rebellious teens, I tried cannabis. It took about a year for me to make the connection between using cannabis and the absence of my normally frequent migraines. I have used cannabis ever since.

I am an avid reader. While perusing an old book on herbal medicine, I read how the little old ladies of Mexico made and used a cannabis/tequila rub on their arthritic hands. Then I met Joey, an epileptic musician. He told me another interesting fact - when he had pot he could cut his medication in half! On a camping trip years later, I smelled an unmistakable odour. Following my nose, I was totally shocked to find a grandmotherly lady in her 70s puffing away on a delicate oriental pipe. "Parkinson's. And the pot's way cheaper than the pills!" Her nephew kept her well supplied, she said. We had a nice chat about various medical uses of cannabis.

Epilepsy, Parkinson's, Arthritis, and my Migraines! What else was it good for? Yet every news article on cannabis that I saw, claimed one new horror after another. Men grew breasts and were impotent. Women became sterile, or miscarried. It made you crazy and murderous. Made you lazy and do nothing. It caused cancer and heart attacks...What I had learned on my own and from others and what I was being told in the press were so different!

What was the truth? I began researching. I printed the first studies up and kept them in a notebook, just as a personal reference. The notebook quickly filled. I started a Word file of the URLs and on July 30 2007, I posted it. It continues to grow.

Here's some of what I have found. All I've done is copy the URLs, then put them all in some semblance order for everyone to use as a reference. Please feel free to share this list with anyone who could benefit from it.
By Dragonfan Owner of  http://grannystormcrowslist.webs.com

You can find the full list here:

http://grannystormcrowslist.webs.com

Read this and most importantly share this with everyone you can

To The Cancer Council Australia - Cannabis Cures Cancer

Hi my name is Michael Davies I am a 31 year old Married  father of 5. It has come to my attention that the Cancer Council with all its money to spend ($61million in NSW over 5 years) managed to miss the fact that Cannabis has been curing peoples cancers all over the world. I have vast amounts of information on the matter and have compiled this info here: www.thecureforcanceraustralia.com and  www.legalizecannabisaustralia.blogspot.com 

I have also shared this info on your facebook page http://www.facebook.com/cancercouncilaustralia

Here is a list of studies:

Cancer Studies:
http://www.ncbi.nlm.nih.gov/pubmed/20053780
http://www.ncbi.nlm.nih.gov/pubmed/16728591
http://www.ncbi.nlm.nih.gov/pubmed/21566064
http://www.ncbi.nlm.nih.gov/pubmed/18833429
Tumor Studies:
http://www.ncbi.nlm.nih.gov/pubmed/18035205
http://www.ncbi.nlm.nih.gov/pubmed/14617682
Clinical Trials:
http://clinicaltrials.gov/ct2/results?term=cannabidiol
http://www.cannabis-med.org/studies/ww_en_db_study_search.php

Sourced from: http://www.medicalmarijuanainc.com

I also have studies showing that there is no link between cannabis and psychosis.
A STUDY by North Staffordshire academics has rejected a link between smoking cannabis and an increase in mental illness.
The research found there were no rises in cases of schizophrenia or psychoses diagnosed in the UK over nine years, during which the use of the drug had grown substantially.
http://www.thisisstaffordshire.co.uk.

There is a company in Australia supplying their Cannabis tincture Mullaways Medical Cannabis Pty Ltd

• Mullaway's Research has already led to groundbreaking Science in the field of Medical Cannabis and results of this Research will soon be Published. The Research opens the way for effective Medical Cannabis Dosage. Based on safe levels of Cannabis/THC consumption Mullaway's has developed easy to use Tables showing the SAFE allowable use of Cannabis.

• This is a major breakthrough for Medical Cannabis. SAFE Cannabis Treatment Plans (for Cancer Patients for example) can now be worked out to help with the disease or symptoms. Tolerance levels can be adjusted so the Psychotropic Effect is not over whelming but manageable or pleasurable.

• Mullaway's Research has removed the demon from the Psychotropic Effect and shows that it is a most valuable Medical Tool. The Research highlights the Psychotropic Effect is very much a pleasurable experience under most circumstances and even if large doses of Cannabis are required for a particular Treatment this can be easily managed.

• Mullaway's Research has made it possible to for the first time to; Design, Cultivate, Trial and Evaluate Cannabis Treatments using SAFE Doses of Cannabis/THC. While the rest of the Medical Cannabis Research world tries to genetically engineer Cannabis without any THC or tries to produce a rich Blend of Cannabinoids/THC from low THC Cannabis Mullaway's Research has already produced the Jewel in the Crown of Medical Cannabis Research;

Australians would like to know what will be done with this information now that I have brought it to your attention. I consider this a life or death matter and hope  something will be done soon.

Regards
Michael Davies

Cannabidiol (CBD) Use In The Anti-Tumor and Anti-Cancer Nutraceutical and Pharmaceutical Industries.

SAN DIEGO, CA--(Business Wire – Sept 2, 2011) - Medical Marijuana Inc (OTC: MJNA) is pleased to announce that studies have proven Cannabidiol (CBD) as an Anti-Tumor and Anti-Cancer agent. Currently Medical Marijuana Inc through CannaBANK has a patent pending on an extraction method from Cannabis and Hemp allowing Cannabidiol (CBD) to be isolated in its pure form. Research shows $200 billion a year is spent to treat Tumors and Cancer. The company is planning on expanding rapidly by allowing a heavily marketed nutraceutical or pharmaceutical company the use of its extraction technology through exclusive license agreements.

“Many qualified companies have shown great interest, and it won’t be long until we license the right one.” said a Medical Marijuana Inc spokesperson.Given the vast number of nutraceutical and pharmaceutical companies across the country, it’s no doubt that CBD can be easily formulated into an array of already heavily marketed products, quickly becoming a major component of health and wellness in the near future.Jared Berry, a CannaBANK executive stated. “Education is the key! The evidence is already overwhelming. Just look at what companies like GW Pharmaceutical’s is accomplishing with Sativex or simply google Cannabidiol (CBD) and the studies and research dedicated to this what’s called a ‘nutritional necessity’ is overwhelmingly obvious.”

List of public studies on Cannabidiol as an Anti-Tumor and Anti-Cancer agent can be found within the following links:

Cancer Studies:

http://www.ncbi.nlm.nih.gov/pubmed/20053780

http://www.ncbi.nlm.nih.gov/pubmed/16728591

http://www.ncbi.nlm.nih.gov/pubmed/21566064

http://www.ncbi.nlm.nih.gov/pubmed/18833429

Tumor Studies:

http://www.ncbi.nlm.nih.gov/pubmed/18035205

http://www.ncbi.nlm.nih.gov/pubmed/14617682

Clinical Trials:

http://clinicaltrials.gov/ct2/results?term=cannabidiol

http://www.cannabis-med.org/studies/ww_en_db_study_search.php

ABOUT MEDICAL MARIJUANA INC (OTC: MJNA)

Our mission is to be the world's premier cannabis and hemp industry innovators, leveraging our team of professionals to source, evaluate, invest in and purchase value-added sustainable companies, while allowing them to keep their integrity and entrepreneurial spirit. We strive to create awareness within our industry, pay homage to the visionaries and activists of the past and present, and provide the platform from which the industry can emerge into a global sustainable economy for all. Medical Marijuana Inc recognizes the vast and unequaled opportunities that exist in the rapidly expanding hemp and medical marijuana industries. The scientific recognition of cannabis has brought legalized marijuana use to the forefront of mainstream discussion, thus opening the door for safe and lucrative investment opportunities.

www.medicalmarijuanainc.com

FORWARD-LOOKING DISCLAIMER

This press release may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties and other factors, which may cause the actual results, performance or achievements of Medical Marijuana Inc to be materially different from the statements made herein.

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE

These statements have not been evaluated by the Food and Drug Administration, products and statements are not intended to diagnose, treat, cure, or prevent any disease.

Contact Information:

Medical Marijuana Inc.2665 Ariane Drive Suite 207

San Diego, CA 92117

888-OTC-MJNA (888-682-6562)

InvestorRelations@MedicalMarijuanaInc.com

A letter to Cancer Australia - Cannabis Cures Cancer

A letter to www.canceraustralia.gov.au "I noticed your mission statement on the front page of your site

"Our Vision

Cancer Australia's vision is to reduce the impact of cancer and improve

the well-being of those diagnosed with cancer in Australia"

I have information that suggests we can remove cancer safely from Australians permanently. I and you have available to us multiple studys, private and government and testemonies of those that have used cannabis oil's and juices to cure thier cancer

e.g MP Amanda Fazio in NSW parliment on 26/8/11 at 3:05pm "Secondly, they are demanding action to allow the use of cannabis by people with a medical certificate. Research has proven that cannabis has anti-cancer properties, and it is time that governments took this issue seriously."

and this study

http://beforeitsnews.com/story/1003/374/Govt_Study_Proves_THC_From_Cannabis_Destroys_Leukemia,_Breast_And_Lung_Cancer_Cells.html

and

http://www.cannabisscience.com/news-a-media/press-releases/220-cannabis-science-extracts-kill-cancer-cells.html

I am sure if you really wanted to cure cancer you would have by now this information has been available for some time and new storys every day. e.g.

http://www.news.com.au/world/pot-cured-brain-cancer-toddler-cash-hydes-father-gave-him-cannabis-oil-to-treat-tumour/story-e6frfkz0-1226050296628

I really hope you take this information seriously. Australians are suffering and dying when they dont have too."

Regards
Michael Davies

A day of Triumph for Australian drug reform

The Hon. AMANDA FAZIO [3.05 p.m.]: Today I inform the House about an organisation that provides a realistic approach to drug law reform. Law Enforcement Against Prohibition [LEAP] Australia was formed in late 2010 by a small group of current and retired law enforcement officers who know that current drug policies in Australia, and internationally, are not working and are impacting on society as a whole. Law Enforcement Against Prohibition Australia is focused on educating the public and policymakers on the harms that current policies are causing and it is heightening the awareness of alternate ways in which to deal with drug abuse and organised crime. All members of the Law Enforcement Against Prohibition Australia Board possess extensive drug and alcohol sector experience.

http://www.parliament.nsw.gov.au

Law Enforcement Against Prohibition Australia does not promote the use of drugs and is deeply concerned about the extent of drug abuse worldwide. It is concerned also about the destructive impact of violent drug gangs and cartels everywhere in the world. Neither problem is remedied by the current policy of drug prohibition. Drug abuse and gang violence flourish in a drug-prohibition environment, just as they did during alcohol prohibition. Law Enforcement Against Prohibition advocates the elimination of the policy of drug prohibition and its replacement by regulated policies based around appropriate restrictions on drug sales.

Drug abuse is a health problem, and drug use should be regulated and subject to restrictions that are similar to those currently applying to alcohol and tobacco. Law Enforcement Against Prohibition Australia recognises that even in a post-prohibition world, all drugs can cause harm and create a potential for addiction, and that this requires appropriate regulation and control. The group believes that all persons suffering from drug abuse afflictions and addiction should be provided with a variety of help, including safe usage education, drug treatment and drug maintenance programs.

Law Enforcement Against Prohibition Australia will support independent research to demonstrate that an end to drug prohibition will control criminal justice expenditures, reduce disease and uptake, and that a fraction of those savings would be more than sufficient to pay for expanded addiction services. Law Enforcement Against Prohibition Australia believes that adult drug use, however dangerous, is a matter of personal freedom as long as it does not impinge on the freedom or safety of others. Adult drug abuse is a health problem and not a law-enforcement matter, provided that the abuse does not harm other people or the property of others. Patrons of Law Enforcement Against Prohibition Australia include the Hon. Michael Kirby, AC, KCMG, Dr Alex Wodak, AM, Director, Alcohol and Drug Service, St. Vincent's Hospital, Bernadette McSherry and Nicholas Cowdrey, QC. On 16 June 2011, the fortieth anniversary of President Richard Nixon's "war on drugs", former President Jimmy Carter, who was the 2002 winner of the Nobel Peace Prize, commented in the New York Times:

In an extraordinary new initiative announced earlier this month, the Global Commission on Drug Policy has made some courageous and profoundly important recommendations in a report on how to bring more effective control over the illicit drug trade. The commission includes the former presidents or prime ministers of five countries, a former secretary general of the United Nations, human rights leaders, and business and government leaders, including Richard Branson, George P. Shultz and Paul A. Volcker. The report describes the total failure of the present global antidrug effort, and in particular America's "war on drugs", which was declared 40 years ago today. It notes that the global consumption of opiates has increased 34.5 percent, cocaine 27 percent and cannabis 8.5 percent from 1998 to 2008. Its primary recommendations are to substitute treatment for imprisonment for people who use drugs but do no harm to others, and to concentrate more coordinated international effort on combating violent criminal organizations rather than nonviolent, low-level offenders.

Currently Law Enforcement Against Prohibition Australia is conducting two campaigns. The first is to regulate rather than prohibit synthetic cannabis. New Zealand has successfully implemented the regulation of synthetic cannabis; we should do likewise. Secondly, they are demanding action to allow the use of cannabis by people with a medical certificate. Research has proven that cannabis has anti-cancer properties, and it is time that governments took this issue seriously.

Currently 19 states of the United States of America allow the use of cannabis for medicinal purposes. In some states the conditions and symptoms eligible are cancer, chronic pain, epilepsy and other conditions characterised by spasms, chronic glaucoma, HIV or AIDS, multiple sclerosis and nausea. I know of a number of cancer suffers who have benefitted from the use of medical cannabis for pain relief, suppressing nausea and appetite stimulation. I support both campaigns.

In Australia in 1985 the Federal and State governments adopted a national drug strategy, which included a pragmatic mixture of prohibition and a stated objective of harm reduction. Harm reduction has been an official part of Australian drugs policy ever since, although most resources by far are devoted to policing and to border patrol attempts at interdiction or supply reduction. Fewer resources are made available for health treatment and drug rehabilitation programs or for preventative public health programs, such as needle exchanges. Australia maintains an extremely low rate of HIV infection among injecting drug users compared to infection rates of 60 per cent or more among injecting drug users in some American cities where needle exchange remains illegal.

I strongly support the campaign by the Law Enforcement Against Prohibition group for elimination of the policy of drug prohibition, which should be replaced by regulated policies based around appropriate restrictions on drug sales. I congratulate those responsible for establishing Law Enforcement Against Prohibition [LEAP] Australia, which builds on the good work that Law Enforcement Against Prohibition [LEAP] has been doing in the United States of America since 2002.

http://www.parliament.nsw.gov.au

Project CBD

Project CBD is a non-profit educational service dedicated to promoting and publicizing research into the medical utility of cannabidiol (CBD) and other components of the Cannabis plant. It was conceived by two journalists who have been covering the medical marijuana movement / industry in the pages of O’Shaughnessy’s. We think the reintroduction of CBD-rich Cannabis into the grassroots supply warrants special focus. We support the Society of Cannabis Clinicians' effort to collect, aggregate and publish data from patients to determine patterns of efficacy or lack of efficacy.               

 — Fred Gardner and Martin Lee

http://projectcbd.org/

Cured: A Cannabis Story (A Film By David Triplett)

Cannabis cured my skin cancer. This is my story.

It has been proven that concentrated cannabis extract oil cures cancer.

Why hasn't The U.S. National Cancer Institute or The American Cancer Society tested Cannabis Oil?. Is it lack of personnel (2,100 USNCI staff members) or limited financial support (USNCI 2010 budget of $5.1 Billion dollars!)

Cannabis Concentrate or extract is the same as Rick Simpson's "Hemp Oil". Hemp seed oil is NOT what Rick Simpson is making and using.

Google "cannabinoids" and "cancer".
Google "endocannabinoids" and "cancer"
Google "THC" and "Cancer".
Google pubmed, go there and look up "endocannabinoids" and "cancer", as well as "cannabinoids" and "cancer".
Google Dr. Robert Dr Robert Melamede and cancer".

Live Free or Die - thats the choice Australians have

Shona Banda sits down and gives a short description of the times and trials that lead her to write her book "Live Free or Die". The book explains how marijuana's essential oils can be collected and used to treat a variety of illnesses, some now thought terminal. She goes on to tell about her personal experience with the oil, and how it saved her life.

National Cancer Institute Cannabis and Cannabinoid Research

Laboratory/Animal/Preclinical Studies

Cannabinoids are a group of 21-carbon–containing terpenophenolic compounds produced uniquely by Cannabis sativa and Cannabis indica species.[1,2] These plant-derived compounds may be referred to as phytocannabinoids. Although delta-9-tetrahydrocannabinol (THC) is the primary psychoactive ingredient, other known compounds with biologic activity are cannabinol, cannabidiol (CBD), cannabichromene, cannabigerol, tetrahydrocannabivarin, and delta-8-THC. CBD, in particular, is thought to have significant analgesic and anti-inflammatory activity without the psychoactive effect (high) of delta-9-THC.

Antitumor Effects

One study in mice and rats suggested that cannabinoids may have a protective effect against the development of certain types of tumors.[3] During this 2-year study, groups of mice and rats were given various doses of THC by gavage. A dose-related decrease in the incidence of hepatic adenoma tumors and hepatocellular carcinoma was observed in the mice. Decreased incidences of benign tumors (polyps and adenomas) in other organs (mammary gland, uterus, pituitary, testis, and pancreas) were also noted in the rats. In another study, delta-9-THC, delta-8-THC, and cannabinol were found to inhibit the growth of Lewis lung adenocarcinoma cells in vitro and in vivo .[4] In addition, other tumors have been shown to be sensitive to cannabinoid-induced growth inhibition.[5-8]

Cannabinoids may cause antitumor effects by various mechanisms, including induction of cell death, inhibition of cell growth, and inhibition of tumor angiogenesis and metastasis.[9-11] Cannabinoids appear to kill tumor cells but do not affect their nontransformed counterparts and may even protect them from cell death. These compounds have been shown to induce apoptosis in glioma cells in culture and induce regression of glioma tumors in mice and rats. Cannabinoids protect normal glial cells of astroglial and oligodendroglial lineages from apoptosis mediated by the CB1 receptor.[12]

In an in vivo model using severe combined immunodeficient mice, subcutaneous tumors were generated by inoculating the animals with cells from human non-small cell lung carcinoma cell lines.[13] Tumor growth was inhibited by 60% in THC-treated mice compared with vehicle-treated control mice. Tumor specimens revealed that THC had antiangiogenic and antiproliferative effects. However, research with immunocompetent murine tumor models has demonstrated immunosuppression and enhanced tumor growth in mice treated with THC.[14,15]

In addition, both plant-derived and endogenous cannabinoids have been studied for anti- inflammatory effects. A mouse study demonstrated that endogenous cannabinoid system signaling is likely to provide intrinsic protection against colonic inflammation.[16] As a result, a hypothesis that phytocannabinoids and endocannabinoids may be useful in the prevention and treatment of colorectal cancer has been developed.[17-20]

Appetite Stimulation

Many animal studies have previously demonstrated that delta-9-THC and other cannabinoids have a stimulatory effect on appetite and increase food intake. It is believed that the endogenous cannabinoid system may serve as a regulator of feeding behavior. The endogenous cannabinoid anandamide potently enhances appetite in mice.[21] Moreover, CB1 receptors in the hypothalamus may be involved in the motivational or reward aspects of eating.[22]

Analgesia

Understanding the mechanism of cannabinoid-induced analgesia has been increased through the study of cannabinoid receptors, endocannabinoids, and synthetic agonists and antagonists. The CB1 receptor is found in both the central nervous system (CNS) and in peripheral nerve terminals. Similar to opioid receptors, increased levels of the CB1 receptor are found in regions of the brain that regulate nociceptive processing.[23] CB2 receptors, located predominantly in peripheral tissue, exist at very low levels in the CNS. With the development of receptor-specific antagonists, additional information about the roles of the receptors and endogenous cannabinoids in the modulation of pain has been obtained.[24,25]

Cannabinoids may also contribute to pain modulation through an anti-inflammatory mechanism; a CB2 effect with cannabinoids acting on mast cell receptors to attenuate the release of inflammatory agents, such as histamine and serotonin, and on keratinocytes to enhance the release of analgesic opioids has been described.[26-28]

References

1. Adams IB, Martin BR: Cannabis: pharmacology and toxicology in animals and humans. Addiction 91 (11): 1585-614, 1996.  [PUBMED Abstract]
   
2. Grotenhermen F, Russo E, eds.: Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential. Binghamton, NY: The Haworth Press, 2002.
   
3. National Toxicology Program .: NTP toxicology and carcinogenesis studies of 1-trans-delta(9)-tetrahydrocannabinol (CAS No. 1972-08-3) in F344 rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser 446 (): 1-317, 1996.  [PUBMED Abstract]
   
4. Bifulco M, Laezza C, Pisanti S, et al.: Cannabinoids and cancer: pros and cons of an antitumour strategy. Br J Pharmacol 148 (2): 123-35, 2006.  [PUBMED Abstract]
   
5. Sánchez C, de Ceballos ML, Gomez del Pulgar T, et al.: Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor. Cancer Res 61 (15): 5784-9, 2001.  [PUBMED Abstract]
   
6. McKallip RJ, Lombard C, Fisher M, et al.: Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 100 (2): 627-34, 2002.  [PUBMED Abstract]
   
7. Casanova ML, Blázquez C, Martínez-Palacio J, et al.: Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 111 (1): 43-50, 2003.  [PUBMED Abstract]
   
8. Blázquez C, González-Feria L, Alvarez L, et al.: Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. Cancer Res 64 (16): 5617-23, 2004.  [PUBMED Abstract]
   
9. Guzmán M: Cannabinoids: potential anticancer agents. Nat Rev Cancer 3 (10): 745-55, 2003.  [PUBMED Abstract]
   
10. Blázquez C, Casanova ML, Planas A, et al.: Inhibition of tumor angiogenesis by cannabinoids. FASEB J 17 (3): 529-31, 2003.  [PUBMED Abstract]
    
11. Vaccani A, Massi P, Colombo A, et al.: Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism. Br J Pharmacol 144 (8): 1032-6, 2005.  [PUBMED Abstract]
    
12. Torres S, Lorente M, Rodríguez-Fornés F, et al.: A combined preclinical therapy of cannabinoids and temozolomide against glioma. Mol Cancer Ther 10 (1): 90-103, 2011.  [PUBMED Abstract]
    
13. Preet A, Ganju RK, Groopman JE: Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene 27 (3): 339-46, 2008.  [PUBMED Abstract]
    
14. Zhu LX, Sharma S, Stolina M, et al.: Delta-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. J Immunol 165 (1): 373-80, 2000.  [PUBMED Abstract]
    
15. McKallip RJ, Nagarkatti M, Nagarkatti PS: Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J Immunol 174 (6): 3281-9, 2005.  [PUBMED Abstract]
    
16. Massa F, Marsicano G, Hermann H, et al.: The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest 113 (8): 1202-9, 2004.  [PUBMED Abstract]
    
17. Patsos HA, Hicks DJ, Greenhough A, et al.: Cannabinoids and cancer: potential for colorectal cancer therapy. Biochem Soc Trans 33 (Pt 4): 712-4, 2005.  [PUBMED Abstract]
    
18. Liu WM, Fowler DW, Dalgleish AG: Cannabis-derived substances in cancer therapy--an emerging anti-inflammatory role for the cannabinoids. Curr Clin Pharmacol 5 (4): 281-7, 2010.  [PUBMED Abstract]
    
19. Malfitano AM, Ciaglia E, Gangemi G, et al.: Update on the endocannabinoid system as an anticancer target. Expert Opin Ther Targets 15 (3): 297-308, 2011.  [PUBMED Abstract]
    
20. Sarfaraz S, Adhami VM, Syed DN, et al.: Cannabinoids for cancer treatment: progress and promise. Cancer Res 68 (2): 339-42, 2008.  [PUBMED Abstract]
    
21. Mechoulam R, Berry EM, Avraham Y, et al.: Endocannabinoids, feeding and suckling--from our perspective. Int J Obes (Lond) 30 (Suppl 1): S24-8, 2006.  [PUBMED Abstract]
    
22. Fride E, Bregman T, Kirkham TC: Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. Exp Biol Med (Maywood) 230 (4): 225-34, 2005.  [PUBMED Abstract]
    
23. Walker JM, Hohmann AG, Martin WJ, et al.: The neurobiology of cannabinoid analgesia. Life Sci 65 (6-7): 665-73, 1999.  [PUBMED Abstract]
    
24. Meng ID, Manning BH, Martin WJ, et al.: An analgesia circuit activated by cannabinoids. Nature 395 (6700): 381-3, 1998.  [PUBMED Abstract]
    
25. Walker JM, Huang SM, Strangman NM, et al.: Pain modulation by release of the endogenous cannabinoid anandamide. Proc Natl Acad Sci U S A 96 (21): 12198-203, 1999.  [PUBMED Abstract]
    
26. Facci L, Dal Toso R, Romanello S, et al.: Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. Proc Natl Acad Sci U S A 92 (8): 3376-80, 1995.  [PUBMED Abstract]
    
27. Ibrahim MM, Porreca F, Lai J, et al.: CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids. Proc Natl Acad Sci U S A 102 (8): 3093-8, 2005.  [PUBMED Abstract]
    
28. Richardson JD, Kilo S, Hargreaves KM: Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 75 (1): 111-9, 1998.  [PUBMED Abstract]

Source: http://www.cancer.gov